Frequency dependence of behavioral modulation by hippocampal electrical stimulation 2 ABBREVIATED TITLE : Behavioral modulation by hippocampal electrical stimulation

نویسندگان

  • Giorgio La Corte
  • Yina Wei
  • Nick Chernyy
  • Bruce J. Gluckman
  • Steven J. Schiff
چکیده

JOURNAL OF NEUROPHYSIOLOGY TITLE PAGE 1 TITLE: Frequency dependence of behavioral modulation by hippocampal electrical stimulation 2 ABBREVIATED TITLE: Behavioral modulation by hippocampal electrical stimulation 3 AUTHORS: Giorgio La Corte, Yina Wei, Nick Chernyy, Bruce J. Gluckman and Steven J. Schiff 4 1. Center for Neural Engineering, Department of Engineering Science and Mechanics, The Pennsylvania State 5 University, State College, PA 16802, USA 6 2. Department of Neurosurgery, The Pennsylvania State University, University Park, PA 16802, USA 7 3. Department of Physics, The Pennsylvania State University, University Park, PA 16802, USA 8 9 CORRESPONDING AUTHOR: Steven J. Schiff 10 W311 Millennium Science Complex, 11 Pollock Road, University Park, PA 16802-2131 12 Email: [email protected]. 13 14 ANY CONFLICT OF INTEREST: None 15 ACKNOWLEDGEMENTS: 16 This study was supported by the National Institutes of Health grant R01MH50006 and K02MH01493. 17 Instrumentation and electrode design was supported under R01EB100157. 18 19 Articles in PresS. J Neurophysiol (November 6, 2013). doi:10.1152/jn.00523.2013

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Increasing the Effectiveness of Carbamazepine by Low Frequency Electrical Stimulation During CA1 Hippocampal Kindling on Seizure Scales in Adult Male Rats: An Experimental Study

  Background and Objectives Nowadays, the application of Low Frequency Stimulations (LFS) has been considered as an alternative treatment in drug-resistant epileptic patients. So, the aim of this study was to determine the co-administration effects of LFS and carbamazepine (CBZ) during epileptogenesis in dorsal hippocampus using electrical Kindling method on seizure scales in adult male rats. ...

متن کامل

Frequency dependence of behavioral modulation by hippocampal electrical stimulation.

Electrical stimulation offers the potential to develop novel strategies for the treatment of refractory medial temporal lobe epilepsy. In particular, direct electrical stimulation of the hippocampus presents the opportunity to modulate pathological dynamics at the ictal focus, although the neuroanatomical substrate of this region renders it susceptible to altering cognition and affective proces...

متن کامل

Effect of acetylcholine receptors on the pain-related electrical activities in the hippocampal CA3 region of morphine-addicted rats

Objective(s):To determine the effect of acetylcholine (ACh), pilocarpine, and atropine on pain evoked responses of pain excited neurons (PEN) and pain inhibited neurons (PIN) in hippocampal CA3 region of morphine addicted rats. Materials and Methods:Female Wistar rats, weighing between 230-260 g were used in this study. Morphine addicted rats were generated by subcutaneous injection of increasi...

متن کامل

The Effect of Sodium Valproate and Low Frequency Electrical Stimulation on Motor Activity During Rapid Kindling of Hippocampal CA1 Region in Adult Male Rat: An Experimental Study

Background and Objectives: Epilepsy is a chronic neurological disorder that requires long treatment with less side effects. Therefore, this study aimed to determine the effect of sodium valproate and electrical stimulation of the brain with low frequency (LFS) on the motor activity of male rat during hippocampus rapid kindling. Material and Methods: In this experimental study, 56 male adult ra...

متن کامل

Biphasic modulation of hippocampal plasticity by behavioral stress and basolateral amygdala stimulation in the rat.

Explicit memory may depend on the hippocampus, whereas the amygdala may be part of an emotional memory system. Priming stimulation of the basolateral group of the amygdala (BLA) resulted in an enhanced long-term potentiation (LTP) in the dentate gyrus (DG) to perforant path (PP) stimulation 30, 90, 150, and 180 min after high-frequency stimulation (HFS). Exposure of rats to a behavioral stress ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013